Basic Information
ID: ALA4336053
Type: Binding
Description: Antagonist activity at human AChR alpha4beta2 transfected in human HEK293 cells assessed as decrease in epibatidine-induced calcium influx at 10 to 100 uM incubated for 1 hr by fluo-4 dye based assay relative to control
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK293
Target: Neuronal acetylcholine receptor; alpha4/beta2(ALA1907589)
Document: ALA4334454
Antagonist activity at human AChR alpha4beta2 transfected in human HEK293 cells assessed as decrease in epibatidine-induced calcium influx at 10 to 100 uM incubated for 1 hr by fluo-4 dye based assay relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4336053
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 292.43 | 4.63 | 4.63 |
| 294.44 | 4.15 | 4.15 |
| 308.43 | 3.37 | 3.37 |