Basic Information
ID: ALA4336162
Type: Functional
Description: Induction of apoptosis in Leishmania major MRHO/IR/75/ER promastigotes assessed as increase in caspase-3 activity at IC50 using Ac-DEVD-pNA as substrate preincubated for 24 hrs followed by substrate addition and measured after 1 hr by spectrophotometric method
Format: BAO_0000218
Organism: Leishmania major
Strain: MRHO/IR/75/ER
Target: Leishmania major(ALA612879)
Document: ALA4334457
Induction of apoptosis in Leishmania major MRHO/IR/75/ER promastigotes assessed as increase in caspase-3 activity at IC50 using Ac-DEVD-pNA as substrate preincubated for 24 hrs followed by substrate addition and measured after 1 hr by spectrophotometric method: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4336162
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 363.44 | 3.16 | 3.16 |
| 377.47 | 2.30 | 2.30 |