Positive allosteric modulation of human TSPO A147T mutant expressed in HEK293 cells assessed as potentiation of PK11195-induced reduction in cell prol...

Basic Information

ID: ALA4337314

Type: Binding

Description: Positive allosteric modulation of human TSPO A147T mutant expressed in HEK293 cells assessed as potentiation of PK11195-induced reduction in cell proliferation at 100 uM after 48 hrs by Brdu incorporation-based ELISA

Format: BAO_0000219

Organism: Homo sapiens

Cell type: HEK293

Target:  Translocator protein(ALA5742)

Document:  ALA4334481

Positive allosteric modulation of human TSPO A147T mutant expressed in HEK293 cells assessed as potentiation of PK11195-induced reduction in cell proliferation at 100 uM after 48 hrs by Brdu incorporation-based ELISA: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
434.546.136.13