Basic Information
ID: ALA4337396
Type: Binding
Description: Selectivity index, ratio of Ki for displacement of [3H]UR-DE257 from human H2R expressed in Sf9 cell membranes co-expressing GsalphaS by competition binding assay to Ki for displacement of 10 nM [3H]-histamine from human H4R expressed in Sf9 cell membranes co-expressing Gia2 and beta1gamma2 by competition binding assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4337396
Ratio Ki
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 505.46 | 2.07 | 2.07 |
| 519.45 | 1.00 | 1.00 |
| 514.43 | 2.22 | 2.22 |
| 477.41 | 1.47 | 1.47 |
| 562.54 | 3.31 | 3.31 |
| 533.47 | 1.34 | 1.34 |
| 477.41 | 1.34 | 1.34 |
| 491.43 | 1.69 | 1.69 |
| 505.46 | 2.08 | 2.08 |
| 519.45 | 0.95 | 0.95 |
| 451.37 | 1.31 | 1.31 |