Basic Information
ID: ALA4337630
Type: Binding
Description: Inhibition of human DNA ligase 1 expressed in Escherichia coli BL21DE3RP cells at 50 uM using 52-mer DNA/25-mer DNA/27-mer DNA as substrate after 30 mins by Cyanin3 dye-based fluorescence assay relative to control
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4337630
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 466.61 | 5.37 | 5.37 |
| 466.65 | 5.77 | 5.77 |
| 470.54 | 6.64 | 6.64 |
| 446.52 | 5.71 | 5.71 |
| 474.53 | 5.03 | 5.03 |
| 418.61 | 5.33 | 5.33 |
| 418.61 | 5.33 | 5.33 |
| 460.55 | 5.39 | 5.39 |
| 474.58 | 5.43 | 5.43 |
| 452.62 | 5.73 | 5.73 |
| 470.54 | 6.64 | 6.64 |
| 466.61 | 5.37 | 5.37 |
| 498.65 | 5.17 | 5.17 |
| 438.60 | 6.05 | 6.05 |
| 518.73 | 8.61 | 8.61 |
| 450.60 | 4.73 | 4.73 |
| 438.60 | 6.05 | 6.05 |
| 466.65 | 5.77 | 5.77 |
| 474.53 | 5.03 | 5.03 |
| 508.73 | 7.36 | 7.36 |
| 426.53 | 4.99 | 4.99 |
| 494.62 | 6.38 | 6.38 |
| 462.62 | 6.98 | 6.98 |
| 484.62 | 5.13 | 5.13 |