Selectivity index, ratio of CC50 for cytotoxicity in MDCK cells assessed as reduction in cell viability incubated for 12 hrs by MTT assay to EC50 for ...

Basic Information

ID: ALA4337901

Type: Toxicity

Description: Selectivity index, ratio of CC50 for cytotoxicity in MDCK cells assessed as reduction in cell viability incubated for 12 hrs by MTT assay to EC50 for antiviral activity against Influenza A virus (A/California/04/2009(H1N1)) ATCC VR-1737 infected in MDCK cells assessed as reduction in virus-induced cytopathic effect incubated for 48 hrs by Cell-titer-Glo luminescence assay

Format: BAO_0000219

Target:  Unchecked(ALA612545)

Document:  ALA4334499

Selectivity index, ratio of CC50 for cytotoxicity in MDCK cells assessed as reduction in cell viability incubated for 12 hrs by MTT assay to EC50 for antiviral activity against Influenza A virus (A/California/04/2009(H1N1)) ATCC VR-1737 infected in MDCK cells assessed as reduction in virus-induced cytopathic effect incubated for 48 hrs by Cell-titer-Glo luminescence assay: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
413.904.264.26
299.250.630.63
367.241.641.64
313.270.930.93
299.202.462.46