Basic Information
ID: ALA4337921
Type: Binding
Description: Allosteric inhibition of N-terminal His-tagged human FPPS expressed in Escherichia coli BL21 (DE3) pre-incubated for 10 mins before addition of GPP and [14C]-IPP by scintillation counting method
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4337921
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 269.26 | 2.58 | 2.58 |
| 335.33 | 3.21 | 3.21 |
| 425.45 | 4.83 | 4.83 |
| 425.45 | 4.83 | 4.83 |
| 459.90 | 5.48 | 5.48 |
| 465.94 | 6.21 | 6.21 |
| 459.90 | 5.48 | 5.48 |
| 477.89 | 5.62 | 5.62 |
| 477.89 | 5.62 | 5.62 |
| 443.44 | 4.96 | 4.96 |
| 441.92 | 5.57 | 5.57 |
| 443.44 | 4.96 | 4.96 |
| 441.92 | 5.57 | 5.57 |
| 465.94 | 6.21 | 6.21 |