Basic Information
ID: ALA4337971
Type: Binding
Description: Potency index, ratio of oleanolic acid IC50 to test compound IC50 for inhibition of HIV1 protease expressed in Escherichia coli using Abz-Ala-Arg-Val-Nle-Tyr(NO2)-Glu-Ala-Nle-NH2 peptide as substrate by FRET assay
Format: BAO_0000019
Organism: Human immunodeficiency virus 1
Target: Protease(ALA2366517)
Document: ALA4334508
Potency index, ratio of oleanolic acid IC50 to test compound IC50 for inhibition of HIV1 protease expressed in Escherichia coli using Abz-Ala-Arg-Val-Nle-Tyr(NO2)-Glu-Ala-Nle-NH2 peptide as substrate by FRET assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4337971
Ratio IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 761.01 | 8.20 | 8.20 |
| 788.12 | 11.42 | 11.42 |
| 789.07 | 8.98 | 8.98 |
| 859.20 | 10.93 | 10.93 |
| 727.00 | 7.44 | 7.44 |
| 789.07 | 8.83 | 8.83 |
| 817.12 | 9.61 | 9.61 |
| 689.93 | 8.69 | 8.69 |
| 887.26 | 11.56 | 11.56 |
| 683.97 | 8.72 | 8.72 |
| 717.99 | 9.47 | 9.47 |
| 669.94 | 8.33 | 8.33 |