Basic Information
ID: ALA4338134
Type: Binding
Description: Inhibition of recombinant MTHFD2 (unknown origin) using THF as substrate incubated for 30 mins in presence of NAD
Format: BAO_0000357
Organism: Homo sapiens
Target: Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial(ALA3621036)
Document: ALA4334513
Inhibition of recombinant MTHFD2 (unknown origin) using THF as substrate incubated for 30 mins in presence of NAD: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4338134
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 363.37 | 3.00 | 3.00 |
| 540.64 | 2.43 | 2.43 |
| 468.51 | 4.42 | 4.42 |
| 486.95 | 2.94 | 2.94 |
| 510.62 | 2.42 | 2.42 |
| 450.49 | 3.02 | 3.02 |
| 611.60 | 2.50 | 2.50 |
| 482.54 | 4.42 | 4.42 |
| 608.64 | 3.71 | 3.71 |
| 447.49 | 2.44 | 2.44 |
| 559.09 | 3.47 | 3.47 |
| 462.50 | 3.16 | 3.16 |
| 486.95 | 2.94 | 2.94 |
| 559.09 | 3.47 | 3.47 |
| 594.61 | 3.32 | 3.32 |
| 436.46 | 2.63 | 2.63 |
| 622.62 | 2.31 | 2.31 |
| 528.61 | 2.56 | 2.56 |
| 589.51 | 3.19 | 3.19 |
| 545.06 | 3.08 | 3.08 |
| 545.06 | 3.08 | 3.08 |
| 573.12 | 3.85 | 3.85 |
| 524.64 | 2.73 | 2.73 |