Selectivity index, ratio of EC50 for cytotoxicity against human MRC5 cells to EC50 for antileishmanial activity against Leishmania donovani MHOM/ET/67...

Basic Information

ID: ALA4338320

Type: Toxicity

Description: Selectivity index, ratio of EC50 for cytotoxicity against human MRC5 cells to EC50 for antileishmanial activity against Leishmania donovani MHOM/ET/67/HU3 amastigotes infected in human THP1 cells

Format: BAO_0000219

Target:  Unchecked(ALA612545)

Document:  ALA4334518

Selectivity index, ratio of EC50 for cytotoxicity against human MRC5 cells to EC50 for antileishmanial activity against Leishmania donovani MHOM/ET/67/HU3 amastigotes infected in human THP1 cells: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
635.587.587.58
691.699.149.14
703.749.849.84
733.779.939.93