Assay Report Card

Basic Information

ID: ALA4338390

Type: ADME

Description: Substrate activity at recombinant full-length mouse CGAS expressed in Escherichia coli BL21 (DE3) assessed as cyclic dinucleotide formation by measuring reaction conversion at 1 mM incubated for 16 hrs in presence of GTP by HPLC-UV analysis

Organism: Mus musculus

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
507.18-1.63-1.63
484.14-2.66-2.66
507.18-1.31-1.31
526.61-0.56-0.56
506.19-1.02-1.02
521.21-1.17-1.17
539.18-3.04-3.04
508.17-1.51-1.51
539.22-2.64-2.64
541.63-0.98-0.98
508.17-2.23-2.23
539.25-0.97-0.97
523.25-1.51-1.51
522.20-2.05-2.05
525.17-0.95-0.95
537.21-2.33-2.33
507.18-1.63-1.63
524.17-1.80-1.80
523.18-1.92-1.92
523.18-1.92-1.92
553.28-0.91-0.91
539.25-0.99-0.99
541.63-0.98-0.98
537.21-1.27-1.27
521.21-1.79-1.79
570.08-0.23-0.23
521.21-1.29-1.29
538.26-0.49-0.49
498.17-2.47-2.47
527.16-0.51-0.51
525.63-0.38-0.38
509.17-0.65-0.65
522.19-1.32-1.32
548.20-0.69-0.69
525.17-1.49-1.49
617.08-0.19-0.19
509.17-0.65-0.65
507.18-1.63-1.63
506.20-1.66-1.66
524.23-0.92-0.92
537.21-1.62-1.62