Basic Information
ID: ALA4338392
Type: ADME
Description: Substrate activity at recombinant full-length human CGAS expressed in Escherichia coli BL21 (DE3) assessed as cyclic dinucleotide formation by measuring reaction conversion at 1 mM incubated for 16 hrs in presence of ATP by HPLC-UV analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4338392
Drug metabolism
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 507.18 | -1.63 | -1.63 |
| 484.14 | -2.66 | -2.66 |
| 507.18 | -1.31 | -1.31 |
| 526.61 | -0.56 | -0.56 |
| 506.19 | -1.02 | -1.02 |
| 521.21 | -1.17 | -1.17 |
| 539.18 | -3.04 | -3.04 |
| 508.17 | -1.51 | -1.51 |
| 539.22 | -2.64 | -2.64 |
| 541.63 | -0.98 | -0.98 |
| 508.17 | -2.23 | -2.23 |
| 539.25 | -0.97 | -0.97 |
| 523.25 | -1.51 | -1.51 |
| 522.20 | -2.05 | -2.05 |
| 525.17 | -0.95 | -0.95 |
| 537.21 | -2.33 | -2.33 |
| 507.18 | -1.63 | -1.63 |
| 524.17 | -1.80 | -1.80 |
| 523.18 | -1.92 | -1.92 |
| 523.18 | -1.92 | -1.92 |
| 553.28 | -0.91 | -0.91 |
| 539.25 | -0.99 | -0.99 |
| 541.63 | -0.98 | -0.98 |
| 537.21 | -1.27 | -1.27 |
| 521.21 | -1.79 | -1.79 |
| 570.08 | -0.23 | -0.23 |
| 521.21 | -1.29 | -1.29 |
| 538.26 | -0.49 | -0.49 |
| 498.17 | -2.47 | -2.47 |
| 527.16 | -0.51 | -0.51 |
| 525.63 | -0.38 | -0.38 |
| 509.17 | -0.65 | -0.65 |
| 522.19 | -1.32 | -1.32 |
| 548.20 | -0.69 | -0.69 |
| 525.17 | -1.49 | -1.49 |
| 617.08 | -0.19 | -0.19 |
| 509.17 | -0.65 | -0.65 |
| 507.18 | -1.63 | -1.63 |
| 506.20 | -1.66 | -1.66 |
| 524.23 | -0.92 | -0.92 |
| 537.21 | -1.62 | -1.62 |