Basic Information
ID: ALA4338443
Type: Binding
Description: Inhibition of human recombinant full length C-terminal His-tagged HDAC3 (1 to 428 residues)/N-terminal GST-tagged NCOR2 (395 to 489 residues) expressed in baculovirus infected Sf9 insect cells at 10 uM using Boc-Lys(epsilon-acetyl)-AMC as substrate incubated for 90 mins by fluorescence assay relative to control
Format: BAO_0000219
Organism: Homo sapiens
Cell type: Sf9
Target: Histone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(ALA2111363)
Document: ALA4334526
Inhibition of human recombinant full length C-terminal His-tagged HDAC3 (1 to 428 residues)/N-terminal GST-tagged NCOR2 (395 to 489 residues) expressed in baculovirus infected Sf9 insect cells at 10 uM using Boc-Lys(epsilon-acetyl)-AMC as substrate incubated for 90 mins by fluorescence assay relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4338443
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 520.63 | 5.10 | 5.10 |
| 530.67 | 4.85 | 4.85 |
| 538.62 | 5.24 | 5.24 |
| 611.75 | 6.21 | 6.21 |
| 576.74 | 6.51 | 6.51 |
| 596.73 | 6.76 | 6.76 |