Basic Information
ID: ALA4338454
Type: Binding
Description: Inhibition of HDAC in human CAL27 cells using Boc-Lys(epsilon-Ac)-AMC as substrate preincubated for 18 hrs followed by substrate addition and measured after 3 hrs by fluorescence assay
Format: BAO_0000219
Organism: Homo sapiens
Target: Histone deacetylase(ALA2093865)
Document: ALA4334526
Inhibition of HDAC in human CAL27 cells using Boc-Lys(epsilon-Ac)-AMC as substrate preincubated for 18 hrs followed by substrate addition and measured after 3 hrs by fluorescence assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4338454
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 264.32 | 2.47 | 2.47 |
| 515.66 | 4.29 | 4.29 |
| 528.70 | 5.46 | 5.46 |
| 514.67 | 5.15 | 5.15 |
| 533.65 | 4.43 | 4.43 |
| 492.66 | 4.98 | 4.98 |
| 520.63 | 5.10 | 5.10 |
| 493.57 | 3.87 | 3.87 |
| 464.61 | 4.36 | 4.36 |
| 500.64 | 4.84 | 4.84 |
| 530.67 | 4.85 | 4.85 |
| 535.65 | 4.55 | 4.55 |
| 514.67 | 5.51 | 5.51 |
| 538.62 | 5.24 | 5.24 |
| 611.75 | 6.21 | 6.21 |
| 576.74 | 6.51 | 6.51 |
| 522.65 | 5.38 | 5.38 |
| 596.73 | 6.76 | 6.76 |