Assay Report Card

Basic Information

ID: ALA4338459

Type: Binding

Description: Inhibition of class 1 HDAC in human CAL27 cells assessed as potentiation of cisplatin-induced cytotoxicity by measuring cisplatin IC50 at 5 uM preincubated for 48 hrs followed by cisplatin addition and measured after 72 hrs by MTT assay (Rvb = 9.79 uM)

Organism: Homo sapiens

Cell type: CAL-27

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
576.746.516.51