Basic Information
ID: ALA4338461
Type: Binding
Description: Inhibition of class 1 HDAC in human CAL27 cells assessed as potentiation of cisplatin-induced cytotoxicity by measuring fold reduction in cisplatin IC50 at 0.5 uM preincubated for 48 hrs followed by cisplatin addition and measured after 72 hrs by MTT assay relative to cisplatin IC50
Organism: Homo sapiens
Cell type: CAL-27
Activity Charts
Bioactivity
Activity Types for Assay ALA4338461
Ratio IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 264.32 | 2.47 | 2.47 |
| 535.65 | 4.55 | 4.55 |