Basic Information
ID: ALA4338464
Type: Binding
Description: Inhibition of class 1 HDAC in human Cal27CisR cells assessed as potentiation of cisplatin-induced cytotoxicity by measuring fold reduction in cisplatin IC50 at 5 uM preincubated for 48 hrs followed by cisplatin addition and measured after 72 hrs by MTT assay relative to cisplatin IC50
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4338464
Ratio IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 576.74 | 6.51 | 6.51 |