Assay Report Card

Basic Information

ID: ALA4338466

Type: Binding

Description: Inhibition of class 1 HDAC in human Cal27CisR cells assessed as potentiation of cisplatin-induced cytotoxicity by measuring fold reduction in cisplatin IC50 at 3.2 uM preincubated for 48 hrs followed by cisplatin addition and measured after 72 hrs by MTT assay relative to cisplatin IC50

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
596.736.766.76