Basic Information
ID: ALA4338539
Type: Binding
Description: Inhibition of class 1 HDAC in human CAL27 cells assessed as potentiation of cisplatin-induced apoptosis by measuring accumulation at sub-G1 phase at 0.5 uM preincubated for 48 hrs followed by 3 uM cisplatin addition and measured after 24 hrs by propidium iodide staining based flow cytometry relative to control
Format: BAO_0000219
Organism: Homo sapiens
Cell type: CAL-27
Target: Class 1 histone deacetylase(ALA4523988)
Document: ALA4334526
Inhibition of class 1 HDAC in human CAL27 cells assessed as potentiation of cisplatin-induced apoptosis by measuring accumulation at sub-G1 phase at 0.5 uM preincubated for 48 hrs followed by 3 uM cisplatin addition and measured after 24 hrs by propidium iodide staining based flow cytometry relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4338539
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 535.65 | 4.55 | 4.55 |