Basic Information
ID: ALA4338583
Type: Binding
Description: Inhibition of N-terminal hexa-histidine tagged Zika virus NS2B/NS3 protease expressed in Escherichia coli BL21-Gold (DE3) using fluorogenic AMC-substituted peptide boc-GRR-7-amino-4-methylcoumarin measured every 30 secs for 10 mins by fluorometric assay
Organism: Zika virus
Activity Charts
Bioactivity
Activity Types for Assay ALA4338583
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 437.47 | 2.64 | 2.64 |
| 444.47 | 5.61 | 5.61 |
| 447.54 | 3.06 | 3.06 |
| 464.48 | 2.41 | 2.41 |
| 419.48 | 2.50 | 2.50 |
| 447.54 | 3.20 | 3.20 |
| 449.51 | 2.51 | 2.51 |
| 393.45 | 1.93 | 1.93 |
| 455.52 | 4.07 | 4.07 |
| 433.51 | 2.81 | 2.81 |
| 464.48 | 2.41 | 2.41 |
| 453.93 | 3.15 | 3.15 |
| 453.93 | 3.15 | 3.15 |
| 447.54 | 3.06 | 3.06 |
| 383.43 | 2.95 | 2.95 |
| 526.60 | 3.61 | 3.61 |
| 419.48 | 2.50 | 2.50 |
| 447.54 | 3.20 | 3.20 |
| 495.58 | 4.17 | 4.17 |
| 464.48 | 2.41 | 2.41 |
| 495.58 | 4.17 | 4.17 |
| 383.43 | 2.95 | 2.95 |
| 396.43 | 3.45 | 3.45 |
| 433.51 | 2.81 | 2.81 |
| 526.60 | 3.61 | 3.61 |
| 464.48 | 2.41 | 2.41 |
| 449.51 | 2.51 | 2.51 |