Basic Information
ID: ALA4338988
Type: ADME
Description: Prodrug conversion assessed as CES1 (unknown origin) mediated aztreonam and beta-lactam ring-opened prodrug intermediate release in 2.5% acetonitrile in 0.05M citrate buffer at 0.5 mg/ml at pH 4.7 at 37degC in presence of CES1 at lower concentration by HPLC analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4338988
Drug metabolism
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 705.69 | 0.66 | 0.66 |
| 677.63 | -0.12 | -0.12 |
| 733.74 | 1.29 | 1.29 |