Inhibition of human N-terminal GST-tagged IDO1 expressed in Escherichia coli Rosetta(DE3) pLysS using L-tryptophan as substrate measured after 1 hr by...

Basic Information

ID: ALA4339112

Type: Binding

Description: Inhibition of human N-terminal GST-tagged IDO1 expressed in Escherichia coli Rosetta(DE3) pLysS using L-tryptophan as substrate measured after 1 hr by fluorescence assay

Format: BAO_0000019

Organism: Homo sapiens

Target: Indoleamine 2,3-dioxygenase(ALA4685)

Document: ALA4334553

Inhibition of human N-terminal GST-tagged IDO1 expressed in Escherichia coli Rosetta(DE3) pLysS using L-tryptophan as substrate measured after 1 hr by fluorescence assay: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA4339112

IC50

Total(26)

Compound Summary

Parent Molecular Weight	ALogP	Polar Surface Area
271.64	1.69	1.69
438.24	0.42	0.42
511.36	1.10	1.10
510.37	1.86	1.86
479.46	1.65	1.65
486.43	0.97	0.97
479.34	0.58	0.58
467.45	1.65	1.65
497.33	0.72	0.72
468.44	0.83	0.83
511.36	1.10	1.10
455.29	1.10	1.10
468.44	0.89	0.89
425.45	-0.31	-0.31
443.44	-0.17	-0.17
450.45	0.75	0.75
439.22	0.39	0.39
447.44	2.76	2.76
454.30	1.86	1.86
444.44	2.35	2.35
414.37	2.52	2.52
331.10	2.23	2.23
483.45	0.40	0.40
347.17	2.94	2.94
495.36	2.10	2.10
434.89	0.47	0.47