Basic Information
ID: ALA4339113
Type: Binding
Description: Inhibition of IDO1 in interferon-gamma-induced human SKOV3 cells assessed as N-formylkynurenine formation using L-tryptophan as substrate measured after 24 hrs by fluorescence assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4339113
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 271.64 | 1.69 | 1.69 |
| 438.24 | 0.42 | 0.42 |
| 511.36 | 1.10 | 1.10 |
| 510.37 | 1.86 | 1.86 |
| 479.46 | 1.65 | 1.65 |
| 486.43 | 0.97 | 0.97 |
| 479.34 | 0.58 | 0.58 |
| 467.45 | 1.65 | 1.65 |
| 497.33 | 0.72 | 0.72 |
| 468.44 | 0.83 | 0.83 |
| 511.36 | 1.10 | 1.10 |
| 455.29 | 1.10 | 1.10 |
| 468.44 | 0.89 | 0.89 |
| 425.45 | -0.31 | -0.31 |
| 443.44 | -0.17 | -0.17 |
| 450.45 | 0.75 | 0.75 |
| 439.22 | 0.39 | 0.39 |
| 447.44 | 2.76 | 2.76 |
| 454.30 | 1.86 | 1.86 |
| 444.44 | 2.35 | 2.35 |
| 414.37 | 2.52 | 2.52 |
| 331.10 | 2.23 | 2.23 |
| 483.45 | 0.40 | 0.40 |
| 347.17 | 2.94 | 2.94 |
| 495.36 | 2.10 | 2.10 |
| 434.89 | 0.47 | 0.47 |