Basic Information
ID: ALA4339144
Type: Binding
Description: Inhibition of recombinant human NEP expressed in insect cells preincubated for 1 hr using Cys(PT14)-Arg-Arg-Leu-Trp-OH as substrate and measured after 1 hr by fluorescence based assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4339144
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 383.44 | 3.36 | 3.36 |
| 369.42 | 3.11 | 3.11 |
| 373.38 | 2.86 | 2.86 |
| 385.42 | 2.73 | 2.73 |
| 419.86 | 3.38 | 3.38 |
| 389.83 | 3.37 | 3.37 |
| 355.39 | 2.72 | 2.72 |
| 417.89 | 4.01 | 4.01 |
| 373.38 | 2.86 | 2.86 |
| 397.47 | 3.75 | 3.75 |
| 417.89 | 4.01 | 4.01 |
| 417.89 | 4.01 | 4.01 |
| 439.39 | 3.62 | 3.62 |
| 439.39 | 3.62 | 3.62 |
| 389.84 | 3.37 | 3.37 |
| 407.83 | 3.51 | 3.51 |
| 373.38 | 2.86 | 2.86 |
| 380.40 | 2.59 | 2.59 |
| 380.40 | 2.59 | 2.59 |
| 389.84 | 3.37 | 3.37 |
| 370.41 | 2.30 | 2.30 |
| 385.42 | 2.73 | 2.73 |
| 383.44 | 3.28 | 3.28 |
| 423.39 | 3.74 | 3.74 |
| 419.86 | 3.38 | 3.38 |
| 412.44 | 2.68 | 2.68 |
| 369.42 | 3.03 | 3.03 |
| 423.39 | 3.74 | 3.74 |
| 399.44 | 3.12 | 3.12 |
| 400.39 | 2.63 | 2.63 |
| 369.42 | 3.03 | 3.03 |