Basic Information
ID: ALA4339286
Type: Binding
Description: Inverse agonist activity at APC-labeled biotinylated RORgammat LBD (unknown origin) assessed as inhibition of N-(2-chloro-6-fluorobenzyl)-N-((20-methoxy-[1,10-biphenyl]-4-yl)methyl)benzenesulfonamide-induced co-activator europium-labeled biotinylated SRC1 peptide recruitment after 1 hr by LANCE-FRET assay relative to control
Format: BAO_0000357
Organism: Homo sapiens
Target: Nuclear receptor ROR-gamma(ALA1741186)
Document: ALA4339183
Inverse agonist activity at APC-labeled biotinylated RORgammat LBD (unknown origin) assessed as inhibition of N-(2-chloro-6-fluorobenzyl)-N-((20-methoxy-[1,10-biphenyl]-4-yl)methyl)benzenesulfonamide-induced co-activator europium-labeled biotinylated SRC1 peptide recruitment after 1 hr by LANCE-FRET assay relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4339286
%max
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 482.63 | 5.05 | 5.05 |
| 440.55 | 5.12 | 5.12 |
| 468.60 | 4.66 | 4.66 |
| 442.56 | 4.13 | 4.13 |
| 482.63 | 5.05 | 5.05 |
| 456.59 | 4.52 | 4.52 |
| 456.59 | 4.52 | 4.52 |
| 454.57 | 5.20 | 5.20 |
| 456.59 | 4.52 | 4.52 |
| 470.62 | 4.91 | 4.91 |
| 442.56 | 4.35 | 4.35 |
| 483.62 | 5.05 | 5.05 |
| 465.64 | 4.29 | 4.29 |
| 482.63 | 5.05 | 5.05 |
| 458.61 | 4.50 | 4.50 |
| 468.60 | 4.66 | 4.66 |
| 454.57 | 4.27 | 4.27 |
| 468.60 | 4.66 | 4.66 |
| 454.57 | 4.27 | 4.27 |
| 476.60 | 4.63 | 4.63 |
| 482.63 | 5.05 | 5.05 |
| 442.56 | 4.35 | 4.35 |
| 458.61 | 4.50 | 4.50 |
| 442.56 | 4.13 | 4.13 |
| 440.55 | 5.12 | 5.12 |
| 476.60 | 4.63 | 4.63 |
| 465.64 | 4.29 | 4.29 |
| 416.53 | 3.64 | 3.64 |
| 470.62 | 4.91 | 4.91 |
| 468.60 | 4.66 | 4.66 |
| 456.59 | 4.52 | 4.52 |
| 483.62 | 5.05 | 5.05 |