Basic Information
ID: ALA4339353
Type: Functional
Description: Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-stimulated TNF-alpha production at 6.0 uM preincubated for 2 hrs followed by LPS stimulaton measured after 22 hrs by ELISA relative to control
Format: BAO_0000219
Organism: Mus musculus
Cell type: RAW264.7
Target: RAW264.7(ALA612557)
Document: ALA4339189
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-stimulated TNF-alpha production at 6.0 uM preincubated for 2 hrs followed by LPS stimulaton measured after 22 hrs by ELISA relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4339353
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 147.27 | 1.30 | 1.30 |
| 502.49 | 4.98 | 4.98 |
| 380.44 | 3.09 | 3.09 |
| 387.25 | 3.96 | 3.96 |
| 518.94 | 5.49 | 5.49 |
| 308.36 | 3.20 | 3.20 |
| 434.49 | 3.96 | 3.96 |
| 344.34 | 3.74 | 3.74 |
| 344.34 | 3.74 | 3.74 |
| 479.49 | 3.87 | 3.87 |
| 459.50 | 3.83 | 3.83 |
| 459.50 | 3.83 | 3.83 |
| 315.38 | 2.93 | 2.93 |
| 358.36 | 4.08 | 4.08 |
| 353.35 | 3.11 | 3.11 |
| 479.49 | 3.87 | 3.87 |
| 491.54 | 3.92 | 3.92 |
| 315.38 | 2.93 | 2.93 |
| 380.44 | 3.09 | 3.09 |
| 380.44 | 3.09 | 3.09 |
| 434.49 | 3.96 | 3.96 |
| 294.33 | 2.86 | 2.86 |
| 380.44 | 3.09 | 3.09 |
| 563.40 | 5.60 | 5.60 |
| 513.39 | 4.72 | 4.72 |
| 358.36 | 4.08 | 4.08 |
| 468.94 | 4.61 | 4.61 |
| 350.42 | 3.08 | 3.08 |
| 541.55 | 4.80 | 4.80 |
| 484.50 | 4.84 | 4.84 |
| 513.39 | 4.72 | 4.72 |
| 308.36 | 3.20 | 3.20 |
| 448.52 | 4.27 | 4.27 |
| 452.48 | 4.10 | 4.10 |
| 468.94 | 4.61 | 4.61 |
| 448.52 | 4.27 | 4.27 |
| 353.35 | 3.11 | 3.11 |
| 498.53 | 5.15 | 5.15 |
| 387.25 | 3.96 | 3.96 |
| 552.50 | 5.86 | 5.86 |
| 529.50 | 4.75 | 4.75 |
| 294.33 | 2.86 | 2.86 |
| 491.54 | 3.92 | 3.92 |
| 358.36 | 4.08 | 4.08 |
| 502.49 | 4.98 | 4.98 |
| 452.48 | 4.10 | 4.10 |
| 358.36 | 4.08 | 4.08 |
| 502.49 | 4.98 | 4.98 |
| 509.51 | 4.71 | 4.71 |
| 350.42 | 3.08 | 3.08 |