Basic Information
ID: ALA4339430
Type: ADME
Description: Inhibition of recombinant human AKR1C2 expressed in Escherichia coli BL21 (D3) using S-tetralol as substrate in presence of NADP+ by UV-spectrophotometric method
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4339430
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 232.28 | 3.00 | 3.00 |
| 364.44 | 4.83 | 4.83 |
| 274.32 | 3.22 | 3.22 |
| 243.06 | 2.25 | 2.25 |
| 364.25 | ||
| 379.46 | 4.57 | 4.57 |
| 363.46 | 4.86 | 4.86 |
| 431.49 | 4.34 | 4.34 |
| 381.45 | 5.00 | 5.00 |
| 533.65 | 5.94 | 5.94 |
| 456.19 | ||
| 361.44 | 4.95 | 4.95 |
| 330.42 | 4.78 | 4.78 |
| 364.44 | 4.83 | 4.83 |
| 393.48 | 4.87 | 4.87 |
| 401.46 | 4.52 | 4.52 |
| 273.33 | 3.25 | 3.25 |
| 381.45 | 5.00 | 5.00 |
| 363.46 | 4.86 | 4.86 |
| 392.50 | 4.29 | 4.29 |
| 382.43 | 4.97 | 4.97 |
| 377.48 | 5.25 | 5.25 |
| 400.47 | 5.59 | 5.59 |
| 363.46 | 4.86 | 4.86 |
| 336.39 | 4.51 | 4.51 |
| 355.48 | 5.20 | 5.20 |
| 363.46 | 4.86 | 4.86 |
| 446.40 | ||
| 379.46 | 4.57 | 4.57 |
| 337.38 | 3.91 | 3.91 |
| 433.43 | 5.12 | 5.12 |
| 356.46 | 5.17 | 5.17 |
| 381.45 | 4.40 | 4.40 |
| 394.47 | 4.84 | 4.84 |
| 393.48 | 4.87 | 4.87 |
| 364.44 | 4.69 | 4.69 |
| 393.48 | 4.27 | 4.27 |
| 401.46 | 4.52 | 4.52 |
| 399.49 | 5.63 | 5.63 |
| 393.48 | 4.87 | 4.87 |
| 401.46 | 4.34 | 4.34 |
| 394.47 | 4.84 | 4.84 |
| 335.40 | 3.49 | 3.49 |
| 336.39 | 4.05 | 4.05 |
| 382.43 | 4.97 | 4.97 |
| 381.45 | 5.00 | 5.00 |
| 401.46 | 4.52 | 4.52 |
| 394.47 | 4.84 | 4.84 |
| 378.47 | 5.22 | 5.22 |
| 433.43 | 5.12 | 5.12 |
| 382.43 | 4.97 | 4.97 |
| 533.65 | 5.94 | 5.94 |
| 379.46 | 4.23 | 4.23 |