Basic Information
ID: ALA4339580
Type: Binding
Description: Inhibition of C-terminal fluorescein-labeled human TCF4 (7 to 51 residues) binding to wild-type C-terminal His6-tagged beta-catenin (138 to 781 residues) expressed in Escherichia coli BL21 DE3 measured after 2.5 hrs by fluorescence polarization assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4339580
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 665.10 | 2.73 | 2.73 |
| 706.20 | 3.79 | 3.79 |
| 742.19 | 4.27 | 4.27 |
| 628.08 | 2.91 | 2.91 |
| 696.54 | 3.76 | 3.76 |
| 667.07 | 2.39 | 2.39 |
| 692.13 | 3.12 | 3.12 |
| 665.10 | 2.73 | 2.73 |
| 726.19 | 3.94 | 3.94 |
| 634.62 | 2.28 | 2.28 |
| 796.16 | 5.16 | 5.16 |
| 796.16 | 5.16 | 5.16 |
| 630.65 | 2.45 | 2.45 |
| 820.19 | 4.44 | 4.44 |
| 661.62 | 2.05 | 2.05 |
| 730.99 | 4.42 | 4.42 |
| 685.52 | 3.45 | 3.45 |
| 810.18 | 5.29 | 5.29 |
| 683.14 | 2.86 | 2.86 |
| 746.60 | 4.92 | 4.92 |
| 687.11 | 2.98 | 2.98 |
| 756.17 | 3.99 | 3.99 |
| 702.76 | 3.11 | 3.11 |
| 665.10 | 2.73 | 2.73 |
| 695.52 | 2.91 | 2.91 |
| 806.16 | 4.05 | 4.05 |
| 780.16 | 5.28 | 5.28 |
| 772.21 | 4.28 | 4.28 |
| 848.24 | 4.92 | 4.92 |
| 651.07 | 2.80 | 2.80 |
| 730.10 | 4.13 | 4.13 |
| 740.21 | 3.98 | 3.98 |
| 666.09 | 2.12 | 2.12 |
| 795.17 | 4.56 | 4.56 |
| 780.16 | 5.28 | 5.28 |
| 730.15 | 4.40 | 4.40 |
| 683.14 | 2.86 | 2.86 |
| 746.60 | 4.92 | 4.92 |
| 712.16 | 4.26 | 4.26 |
| 730.15 | 4.40 | 4.40 |
| 651.07 | 2.80 | 2.80 |
| 685.52 | 3.45 | 3.45 |
| 854.63 | 5.10 | 5.10 |
| 696.54 | 3.76 | 3.76 |
| 651.07 | 2.80 | 2.80 |
| 667.07 | 2.39 | 2.39 |
| 712.16 | 4.26 | 4.26 |
| 819.20 | 3.84 | 3.84 |
| 746.60 | 4.92 | 4.92 |
| 742.19 | 4.27 | 4.27 |
| 805.17 | 3.45 | 3.45 |
| 742.19 | 4.27 | 4.27 |
| 646.65 | 2.15 | 2.15 |
| 742.19 | 4.27 | 4.27 |
| 795.17 | 4.56 | 4.56 |
| 742.19 | 4.27 | 4.27 |
| 684.62 | 3.16 | 3.16 |
| 730.15 | 4.40 | 4.40 |