Basic Information
ID: ALA4339621
Type: Binding
Description: Negative allosteric modulation of recombinant rat GluN1/GluN2C expressed in Xenopus laevis oocytes assessed as inhibition of glutamate/glycine-induced current response at 10 uM at -40 mV holding potential by two-electrode voltage clamp method relative to glutamate/glycine
Organism: Rattus norvegicus
Activity Charts
Bioactivity
Activity Types for Assay ALA4339621
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 461.90 | 3.03 | 3.03 |
| 312.37 | 3.78 | 3.78 |
| 351.41 | 4.26 | 4.26 |