Basic Information
ID: ALA4339625
Type: Binding
Description: Negative allosteric modulation of recombinant rat GluN1/GluN2C expressed in Xenopus laevis oocytes assessed as inhibition of glutamate/glycine-induced current response at 30 uM at -40 mV holding potential by two-electrode voltage clamp method relative to glutamate/glycine
Organism: Rattus norvegicus
Activity Charts
Bioactivity
Activity Types for Assay ALA4339625
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 461.90 | 3.03 | 3.03 |
| 496.59 | 3.70 | 3.70 |
| 496.59 | 3.70 | 3.70 |
| 495.60 | 4.30 | 4.30 |
| 548.04 | 5.09 | 5.09 |
| 459.55 | 4.75 | 4.75 |
| 495.60 | 4.30 | 4.30 |
| 482.56 | 3.65 | 3.65 |
| 481.57 | 4.26 | 4.26 |
| 481.57 | 4.26 | 4.26 |
| 482.56 | 3.65 | 3.65 |
| 548.04 | 5.09 | 5.09 |