Basic Information
ID: ALA4339630
Type: Binding
Description: Negative allosteric modulation of recombinant rat GluN1/GluN2D expressed in Xenopus laevis oocytes assessed as inhibition of glutamate/glycine-induced current response at 6 uM at -40 mV holding potential by two-electrode voltage clamp method relative to glutamate/glycine
Format: BAO_0000219
Organism: Rattus norvegicus
Target: Ionotropic glutamate receptor NMDA 1/2D(ALA3038506)
Document: ALA4339195
Negative allosteric modulation of recombinant rat GluN1/GluN2D expressed in Xenopus laevis oocytes assessed as inhibition of glutamate/glycine-induced current response at 6 uM at -40 mV holding potential by two-electrode voltage clamp method relative to glutamate/glycine: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4339630
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 461.90 | 3.03 | 3.03 |
| 425.85 | 3.48 | 3.48 |