Basic Information
ID: ALA4339633
Type: Binding
Description: Negative allosteric modulation of recombinant rat GluN1/GluN2A expressed in Xenopus laevis oocytes assessed as inhibition of glutamate/glycine-induced current response at 30 uM at -40 mV holding potential by two-electrode voltage clamp method relative to glutamate/glycine
Organism: Rattus norvegicus
Activity Charts
Bioactivity
Activity Types for Assay ALA4339633
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 459.55 | 4.75 | 4.75 |
| 495.60 | 4.30 | 4.30 |
| 425.85 | 3.48 | 3.48 |