Assay Report Card

Basic Information

ID: ALA4339640

Type: Binding

Description: Negative allosteric modulation of rat GluK2 expressed in Xenopus laevis oocytes assessed as inhibition of glutamate-induced current response at 30 uM at -40 mV holding potential in presence of concanavalin A by two-electrode voltage clamp method relative to glutamate alone

Organism: Rattus norvegicus

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
495.604.304.30
351.414.264.26