Basic Information
ID: ALA4339650
Type: Binding
Description: Negative allosteric modulation of recombinant human GluN1a/GluN2A expressed in CHO-T-REx cells assessed as inhibition of glutamate/glycine-induced response preincubated for 5 mins followed by glutamate/glycine addition and measured after 5 mins by calcium 5 dye based FLIPR TETRA analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4339650
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 376.34 | 2.69 | 2.69 |
| 359.35 | 4.00 | 4.00 |