Ex vivo receptor occupancy at GluN2B receptor in Sprague-Dawley rat brain assessed as reduction in 3-[3H] 1-(azetidin-1-yl)-2-[6-(4-fluoro-3-methyl-ph...

Basic Information

ID: ALA4339674

Type: Functional

Description: Ex vivo receptor occupancy at GluN2B receptor in Sprague-Dawley rat brain assessed as reduction in 3-[3H] 1-(azetidin-1-yl)-2-[6-(4-fluoro-3-methyl-phenyl)pyrrolo[3,2-b]pyridin-1-yl]ethanone receptor labeling at 10 mg/kg, po measured after 0.5 hrs by autoradiography

Format: BAO_0000218

Organism: Rattus norvegicus

Strain: Sprague-Dawley

Target:  Rattus norvegicus(ALA376)

Document:  ALA4339196

Ex vivo receptor occupancy at GluN2B receptor in Sprague-Dawley rat brain assessed as reduction in 3-[3H] 1-(azetidin-1-yl)-2-[6-(4-fluoro-3-methyl-phenyl)pyrrolo[3,2-b]pyridin-1-yl]ethanone receptor labeling at 10 mg/kg, po measured after 0.5 hrs by autoradiography: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
311.363.243.24
293.373.103.10
333.843.813.81
353.373.873.87