Basic Information
ID: ALA4339685
Type: ADME
Description: Glutathione reactivity in human liver microsomes assessed as +GSH-2H+2O adduct formation at 10 uM measured after 60 mins by LC-MS/MS analysis
Format: BAO_0000251
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsome
Target: ADMET(ALA612558)
Document: ALA4339196
Glutathione reactivity in human liver microsomes assessed as +GSH-2H+2O adduct formation at 10 uM measured after 60 mins by LC-MS/MS analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4339685
Drug metabolism
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 311.36 | 3.24 | 3.24 |
| 293.37 | 3.10 | 3.10 |
| 333.84 | 3.81 | 3.81 |
| 353.37 | 3.87 | 3.87 |
| 347.34 | 3.81 | 3.81 |