Basic Information
ID: ALA4339686
Type: Binding
Description: Negative allosteric modulation of recombinant human GluA1 flop isoform/TARPgamma8 expressed in HEK293 cells assessed as inhibition of glutamate-induced calcium flux by calcium 5/6 dye based FLIPR assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK293
Target: GRIA1/CACNG8(ALA4296110)
Document: ALA4339197
Negative allosteric modulation of recombinant human GluA1 flop isoform/TARPgamma8 expressed in HEK293 cells assessed as inhibition of glutamate-induced calcium flux by calcium 5/6 dye based FLIPR assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4339686
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 438.92 | 3.40 | 3.40 |
| 304.32 | 4.54 | 4.54 |