Basic Information
ID: ALA4339816
Type: Binding
Description: Inhibition of human MOLT4 cell-derived PDE10A using [3H]cAMP as substrate measured after 2 hrs in presence of rolipram/milrinone by topcount method
Format: BAO_0000357
Organism: Homo sapiens
Target: Phosphodiesterase 10A(ALA4409)
Document: ALA4339202
Inhibition of human MOLT4 cell-derived PDE10A using [3H]cAMP as substrate measured after 2 hrs in presence of rolipram/milrinone by topcount method: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4339816
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 339.39 | 3.86 | 3.86 |
| 446.53 | 5.33 | 5.33 |
| 460.56 | 5.64 | 5.64 |
| 409.51 | 6.33 | 6.33 |
| 381.46 | 5.76 | 5.76 |
| 389.48 | 4.71 | 4.71 |
| 350.42 | 5.37 | 5.37 |
| 343.41 | 4.88 | 4.88 |
| 375.45 | 4.37 | 4.37 |
| 384.46 | 6.27 | 6.27 |
| 361.43 | 4.11 | 4.11 |
| 395.49 | 6.07 | 6.07 |
| 444.30 | 5.61 | 5.61 |
| 386.88 | 5.41 | 5.41 |
| 395.49 | 6.07 | 6.07 |
| 395.49 | 6.07 | 6.07 |
| 360.44 | 5.21 | 5.21 |