Basic Information
ID: ALA4339971
Type: Functional
Description: Antagonist activity at D2 receptor (unknown origin) expressed in CHOK1 cells assessed as inhibition of dopamine-induced calcium flux preincubated for 60 mins at 37 degC followed by 15 mins incubation under room temperature and subsequent dopamine addition measured after 20 secs for 100 secs by calcium-4 dye based FLIPR assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4339971
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 287.79 | 3.67 | 3.67 |
| 355.43 | 3.38 | 3.38 |
| 367.40 | 3.00 | 3.00 |
| 543.57 | 4.63 | 4.63 |
| 487.51 | 0.26 | 0.26 |
| 487.51 | 0.26 | 0.26 |
| 341.41 | 3.07 | 3.07 |
| 327.38 | 2.77 | 2.77 |
| 385.46 | 4.65 | 4.65 |
| 313.35 | 2.47 | 2.47 |
| 371.43 | 3.08 | 3.08 |
| 295.34 | 2.78 | 2.78 |
| 341.41 | 3.07 | 3.07 |
| 341.41 | 3.07 | 3.07 |
| 355.39 | 2.79 | 2.79 |
| 325.36 | 2.79 | 2.79 |
| 311.38 | 3.06 | 3.06 |
| 295.34 | 2.78 | 2.78 |
| 371.43 | 3.08 | 3.08 |