Assay Report Card

Basic Information

ID: ALA4340058

Type: Binding

Description: Inhibition of C-terminal His tagged purified recombinant PCSK9 D374Y mutant (unknown origin) and LDLR protein-protein interaction expressed in human HepG2 cells assessed as LDLR protein expression level at cell surface at 350 uM incubated for 2 hrs by in-cell western analysis (Rvb = 39.6 +/- 0.7%)

Organism: Homo sapiens

Cell type: HepG2

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
1581.66