Basic Information
ID: ALA4340216
Type: Binding
Description: Inhibition of pH 6.25-stimulated mouse ASIC1a/2a heterodimer expressed in CHOK1 cells assessed as reduction in channel activation by VSD fluorescence assay
Organism: Mus musculus
Activity Charts
Bioactivity
Activity Types for Assay ALA4340216
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 281.32 | 2.37 | 2.37 |
| 307.37 | 4.26 | 4.26 |
| 291.33 | 4.17 | 4.17 |
| 309.35 | 2.69 | 2.69 |
| 296.35 | 3.15 | 3.15 |
| 309.39 | 4.06 | 4.06 |
| 309.39 | 3.80 | 3.80 |
| 311.82 | 4.27 | 4.27 |
| 309.39 | 4.31 | 4.31 |
| 307.37 | 4.26 | 4.26 |
| 309.35 | 2.69 | 2.69 |
| 345.37 | 4.63 | 4.63 |
| 306.41 | 3.07 | 3.07 |
| 296.35 | 3.15 | 3.15 |
| 295.36 | 3.75 | 3.75 |
| 309.39 | 3.81 | 3.81 |
| 323.38 | 3.03 | 3.03 |
| 307.37 | 3.90 | 3.90 |
| 307.40 | 3.62 | 3.62 |
| 295.36 | 3.75 | 3.75 |
| 307.37 | 3.90 | 3.90 |
| 291.40 | 3.92 | 3.92 |
| 292.39 | 3.32 | 3.32 |
| 295.36 | 3.75 | 3.75 |
| 267.31 | 3.14 | 3.14 |