Basic Information
ID: ALA4340228
Type: Binding
Description: Inhibition of NOTCH1 signalling in human KOPTK1 cells harboring activating Notch1 gene mutations assessed as reduction in N1Val protein expression at 2.5 uM incubated for 36 hrs by Western blot analysis
Organism: Homo sapiens
Cell type: KOPTK1
Activity Charts
Bioactivity
Activity Types for Assay ALA4340228
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 270.28 | 3.00 | 3.00 |
| 284.31 | 3.31 | 3.31 |
| 298.34 | 3.09 | 3.09 |
| 238.29 | 3.60 | 3.60 |
| 326.39 | 3.70 | 3.70 |
| 326.39 | 3.70 | 3.70 |