Basic Information
ID: ALA4340229
Type: Binding
Description: Inhibition of NOTCH1 signalling in human KOPTK1 cells harboring activating Notch1 gene mutations assessed as reduction in DELTEX1 mRNA expression at 2.5 uM incubated for 36 hrs by RT-PCR analysis
Organism: Homo sapiens
Cell type: KOPTK1
Activity Charts
Bioactivity
Activity Types for Assay ALA4340229
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 270.28 | 3.00 | 3.00 |
| 284.31 | 3.31 | 3.31 |
| 298.34 | 3.09 | 3.09 |
| 238.29 | 3.60 | 3.60 |
| 326.39 | 3.70 | 3.70 |
| 326.39 | 3.70 | 3.70 |