Basic Information
ID: ALA4340981
Type: Binding
Description: Ratio of EC50 of PIM1 in human NCI-H1299 cells assessed as reduction in BAD phosphorylation at Ser-112 residue to IC50 of His tagged human recombinant PIM1
Format: BAO_0000219
Organism: Homo sapiens
Target: Serine/threonine-protein kinase PIM1(ALA2147)
Document: ALA4340512
Ratio of EC50 of PIM1 in human NCI-H1299 cells assessed as reduction in BAD phosphorylation at Ser-112 residue to IC50 of His tagged human recombinant PIM1: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4340981
Ratio
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 422.41 | 3.13 | 3.13 |
| 405.42 | 4.05 | 4.05 |
| 429.53 | 3.18 | 3.18 |
| 444.54 | 2.97 | 2.97 |
| 414.51 | 4.52 | 4.52 |
| 462.53 | 2.98 | 2.98 |
| 482.95 | 3.33 | 3.33 |
| 448.51 | 2.67 | 2.67 |
| 417.47 | 2.76 | 2.76 |
| 429.53 | 4.16 | 4.16 |
| 536.64 | 4.03 | 4.03 |
| 430.52 | 2.67 | 2.67 |
| 482.95 | 3.33 | 3.33 |
| 431.50 | 3.01 | 3.01 |
| 458.57 | 3.36 | 3.36 |
| 416.49 | 2.10 | 2.10 |
| 415.50 | 3.91 | 3.91 |
| 443.56 | 4.55 | 4.55 |
| 484.49 | 2.95 | 2.95 |
| 466.50 | 2.81 | 2.81 |
| 444.54 | 2.92 | 2.92 |
| 415.50 | 3.91 | 3.91 |
| 430.52 | 2.58 | 2.58 |
| 474.57 | 2.60 | 2.60 |
| 402.46 | 1.58 | 1.58 |
| 430.51 | 3.61 | 3.61 |
| 466.50 | 2.81 | 2.81 |
| 458.57 | 3.36 | 3.36 |
| 444.50 | 2.11 | 2.11 |
| 448.51 | 2.67 | 2.67 |
| 430.52 | 2.58 | 2.58 |
| 416.49 | 2.33 | 2.33 |