Basic Information
ID: ALA4341305
Type: Binding
Description: Poison activity at recombinant human TOP1 expressed in baculovirus infected Sf9 insect cells assessed as decrease in relaxed supercoiled pBS(SK+) DNA mobility at 100 uM measured after 30 mins by ethidium bromide staining based agarose gel electrophoresis relative to control
Format: BAO_0000219
Organism: Homo sapiens
Cell type: Sf9
Target: DNA topoisomerase I(ALA1781)
Document: ALA4340526
Poison activity at recombinant human TOP1 expressed in baculovirus infected Sf9 insect cells assessed as decrease in relaxed supercoiled pBS(SK+) DNA mobility at 100 uM measured after 30 mins by ethidium bromide staining based agarose gel electrophoresis relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4341305
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 431.50 | 3.70 | 3.70 |
| 461.52 | 3.71 | 3.71 |