Basic Information
ID: ALA4341343
Type: Binding
Description: Inhibition of JAK2 (unknown origin) using TK-substrate-biotin as substrate preincubated for 5 mins followed by substrate addition and measured by 30 mins by HTRF assay
Format: BAO_0000357
Organism: Homo sapiens
Target: Tyrosine-protein kinase JAK2(ALA2971)
Document: ALA4340527
Inhibition of JAK2 (unknown origin) using TK-substrate-biotin as substrate preincubated for 5 mins followed by substrate addition and measured by 30 mins by HTRF assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4341343
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 312.38 | 1.54 | 1.54 |
| 371.43 | 1.10 | 1.10 |
| 463.49 | 3.61 | 3.61 |
| 494.50 | 3.70 | 3.70 |
| 482.61 | 2.86 | 2.86 |
| 384.46 | 3.11 | 3.11 |
| 505.55 | 3.22 | 3.22 |
| 520.59 | 4.70 | 4.70 |
| 447.54 | 3.92 | 3.92 |
| 450.52 | 3.29 | 3.29 |
| 391.41 | 3.73 | 3.73 |
| 497.62 | 3.58 | 3.58 |
| 471.57 | 3.34 | 3.34 |
| 461.57 | 4.17 | 4.17 |
| 520.59 | 4.70 | 4.70 |
| 418.41 | 3.50 | 3.50 |
| 486.58 | 4.06 | 4.06 |
| 402.45 | 3.25 | 3.25 |
| 373.42 | 3.59 | 3.59 |
| 458.52 | 3.42 | 3.42 |