Basic Information
ID: ALA4341687
Type: Binding
Description: Inhibition of human recombinant N-terminal hexahistidine tagged JAK2 JH1 catalytic domain (835 to 1132 residues) expressed in baculovirus infected Sf9 cells using Tyr6 peptide as substrate incubated for 30 secs under shaking condition measured after 1 hr by Z'-LYTE assay
Organism: Homo sapiens
Cell type: Sf9
Activity Charts
Bioactivity
Activity Types for Assay ALA4341687
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 436.32 | 4.48 | 4.48 |
| 450.35 | 5.04 | 5.04 |
| 306.37 | 3.47 | 3.47 |
| 451.33 | 5.46 | 5.46 |
| 450.35 | 5.04 | 5.04 |
| 462.36 | 4.72 | 4.72 |
| 378.23 | 5.31 | 5.31 |
| 426.92 | 4.67 | 4.67 |
| 426.92 | 4.67 | 4.67 |
| 425.94 | 5.73 | 5.73 |
| 425.94 | 5.73 | 5.73 |
| 445.93 | 4.39 | 4.39 |
| 411.48 | 3.74 | 3.74 |
| 449.36 | 5.07 | 5.07 |
| 342.80 | 5.26 | 5.26 |
| 363.47 | 3.59 | 3.59 |
| 415.90 | 4.38 | 4.38 |
| 432.36 | 4.90 | 4.90 |
| 332.77 | 3.99 | 3.99 |
| 464.37 | 5.43 | 5.43 |
| 369.51 | 3.80 | 3.80 |
| 462.36 | 4.72 | 4.72 |