Basic Information
ID: ALA4341772
Type: Binding
Description: Inhibition of human MNK1 using CREBtide substrate by gamma-[32P]-ATP competitive inhibition assay
Format: BAO_0000357
Organism: Homo sapiens
Target: MAP kinase-interacting serine/threonine-protein kinase MNK1(ALA4718)
Document: ALA4340542
Inhibition of human MNK1 using CREBtide substrate by gamma-[32P]-ATP competitive inhibition assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4341772
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 244.23 | 1.82 | 1.82 |
| 434.92 | 5.52 | 5.52 |
| 476.51 | 4.60 | 4.60 |
| 560.46 | 5.16 | 5.16 |
| 503.51 | 4.37 | 4.37 |
| 488.54 | 4.47 | 4.47 |
| 470.55 | 4.33 | 4.33 |
| 420.51 | 5.14 | 5.14 |
| 475.41 | 5.80 | 5.80 |
| 487.01 | 4.84 | 4.84 |
| 519.97 | 4.88 | 4.88 |
| 476.58 | 4.39 | 4.39 |
| 506.53 | 4.61 | 4.61 |
| 310.43 | 3.73 | 3.73 |
| 551.44 | 5.53 | 5.53 |
| 299.37 | 4.45 | 4.45 |
| 330.84 | 4.08 | 4.08 |
| 393.29 | 4.32 | 4.32 |
| 485.52 | 4.23 | 4.23 |
| 505.00 | 4.98 | 4.98 |
| 375.30 | 4.19 | 4.19 |
| 386.52 | 5.30 | 5.30 |
| 500.58 | 4.34 | 4.34 |
| 492.96 | 5.11 | 5.11 |
| 314.39 | 3.56 | 3.56 |
| 497.56 | 4.10 | 4.10 |
| 494.50 | 4.74 | 4.74 |
| 515.55 | 4.24 | 4.24 |
| 482.59 | 4.20 | 4.20 |
| 487.01 | 4.84 | 4.84 |
| 330.84 | 4.08 | 4.08 |
| 326.43 | 3.43 | 3.43 |
| 469.38 | 5.89 | 5.89 |
| 510.95 | 5.25 | 5.25 |
| 315.83 | 4.97 | 4.97 |
| 446.55 | 4.38 | 4.38 |
| 492.96 | 5.11 | 5.11 |
| 451.39 | 5.76 | 5.76 |
| 546.43 | 4.85 | 4.85 |
| 406.94 | 5.65 | 5.65 |
| 344.42 | 3.57 | 3.57 |
| 390.49 | 5.13 | 5.13 |
| 430.51 | 4.88 | 4.88 |
| 488.54 | 4.47 | 4.47 |
| 521.49 | 5.31 | 5.31 |
| 472.54 | 4.77 | 4.77 |
| 555.40 | 5.36 | 5.36 |
| 549.45 | 5.09 | 5.09 |
| 402.52 | 5.00 | 5.00 |
| 332.38 | 3.70 | 3.70 |
| 481.56 | 4.40 | 4.40 |
| 315.83 | 4.97 | 4.97 |
| 348.83 | 4.22 | 4.22 |
| 537.41 | 5.22 | 5.22 |
| 465.42 | 6.06 | 6.06 |
| 501.98 | 4.74 | 4.74 |
| 545.48 | 5.26 | 5.26 |
| 525.45 | 5.15 | 5.15 |
| 458.59 | 4.25 | 4.25 |
| 418.47 | 5.01 | 5.01 |
| 479.38 | 5.63 | 5.63 |
| 481.00 | 5.04 | 5.04 |
| 507.46 | 5.01 | 5.01 |
| 389.32 | 4.49 | 4.49 |
| 461.39 | 5.49 | 5.49 |
| 442.59 | 4.55 | 4.55 |
| 360.28 | 5.08 | 5.08 |
| 396.52 | 5.04 | 5.04 |
| 531.46 | 4.95 | 4.95 |
| 463.01 | 4.90 | 4.90 |
| 295.41 | 4.62 | 4.62 |
| 311.41 | 4.32 | 4.32 |
| 416.93 | 5.38 | 5.38 |
| 416.93 | 5.38 | 5.38 |
| 412.52 | 4.74 | 4.74 |
| 466.59 | 4.50 | 4.50 |
| 406.94 | 5.65 | 5.65 |
| 501.98 | 4.74 | 4.74 |
| 400.48 | 4.87 | 4.87 |
| 464.54 | 4.52 | 4.52 |
| 463.01 | 4.90 | 4.90 |
| 424.93 | 5.79 | 5.79 |
| 564.42 | 4.99 | 4.99 |
| 408.48 | 5.27 | 5.27 |