Basic Information
ID: ALA4341825
Type: Binding
Description: Antagonist activity at GST-tagged FXR LBD (unknown origin) assessed as inhibition of GW4064-induced fluorecein-labeled SRC2-2 coactivator recruitment by Lanthascreen TR-FRET assay
Format: BAO_0000357
Organism: Homo sapiens
Target: Bile acid receptor FXR(ALA2047)
Document: ALA4340545
Antagonist activity at GST-tagged FXR LBD (unknown origin) assessed as inhibition of GW4064-induced fluorecein-labeled SRC2-2 coactivator recruitment by Lanthascreen TR-FRET assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4341825
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 593.73 | 6.47 | 6.47 |
| 615.73 | 6.91 | 6.91 |
| 611.72 | 6.61 | 6.61 |
| 541.61 | 6.30 | 6.30 |
| 629.78 | 6.02 | 6.02 |
| 551.05 | 7.08 | 7.08 |
| 516.60 | 6.43 | 6.43 |
| 553.71 | 6.82 | 6.82 |
| 593.73 | 6.47 | 6.47 |
| 538.69 | 6.43 | 6.43 |
| 608.74 | 6.40 | 6.40 |
| 607.76 | 5.88 | 5.88 |
| 559.63 | 5.53 | 5.53 |
| 635.81 | 7.59 | 7.59 |
| 579.75 | 6.94 | 6.94 |
| 623.75 | 6.48 | 6.48 |
| 673.79 | 8.06 | 8.06 |
| 628.17 | 7.12 | 7.12 |
| 593.73 | 6.47 | 6.47 |
| 601.71 | 6.56 | 6.56 |
| 599.78 | 6.39 | 6.39 |