ID: ALA4341884
Type: Binding
Description: Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as inhibition of BzATP-induced YO PRO dye uptake preincubated for 20 mins followed by YO PRO dye and BzATP addition measured after 30 mins by fluorescence assay
Organism: Homo sapiens
Cell type: HEK293
Bioactivity
Activity Types for Assay ALA4341884
IC50
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
425.88 | 4.99 | 4.99 |
441.88 | 4.11 | 4.11 |
445.01 | 3.70 | 3.70 |
460.02 | 4.16 | 4.16 |
425.88 | 4.99 | 4.99 |
451.95 | 4.65 | 4.65 |
397.85 | 3.85 | 3.85 |
466.96 | 3.60 | 3.60 |
450.96 | 4.58 | 4.58 |
194.08 | ||
411.88 | 4.50 | 4.50 |
338.79 | 4.44 | 4.44 |
425.88 | 4.99 | 4.99 |
419.93 | 4.11 | 4.11 |
441.88 | 4.11 | 4.11 |
412.86 | 4.47 | 4.47 |
407.89 | 5.04 | 5.04 |
404.89 | 6.01 | 6.01 |
450.96 | 4.58 | 4.58 |
406.90 | 6.10 | 6.10 |